A study published in Clinical Nutrition shows that curcumin may lower inflammation, which contributes to a wide range of illnesses such as heart disease and joint pain.
The researchers recruited 117 participants who had been diagnosed withmetabolic syndrome. Half of the participants were given pills containing oneÂ gram of curcumin powder, and the other half were given a placebo pill. AllÂ the participants took the supplements every day for eight weeks. At theÂ beginning of the study and again at the end, the researchers measured levelsÂ of three blood markers of inflammation-C-reactive protein (CRP), superoxideÂ dismutase (SOD), and malondialdehyde (MDA).
The researchers found that the participants who took curcumin had improvedÂ blood levels of all three biomarkers as well as reduced fasting blood sugarÂ and hemoglobin A1c, a measure of long-term blood sugar levels. The placeboÂ group had higher glucose and levels of one of the inflammation markers, andÂ no changes in the other markers.
In addition, due to CRP's importance as a risk marker and risk factor ofÂ cardiovascular disease, a random-effects meta-analysis of clinical trialsÂ was performed to estimate the overall impact of curcuminoid therapy onÂ circulating concentrations of CRP. The results from eight previous studiesÂ confirmed that curcumin had shown a significant reduction of CRP
concentrations in a total of 281 patients.